Merbliss, are you talking about soft-proof profiles?? Working in RGB is perfect for "on-screen" work. It's primary purpose is to specify the RGB space you want Photoshop to simulate. (Bear in mind the RGB space looks different between MAC and PC...) Many of the other profiles are for "soft-proofing" your document. (these are the one that list a specific printer brand and model) Traditionally, you would print a "hard copy" proof of your document to see how the colors look. Using CMS (color management system) you can use the color profiles to "soft" proof the image right on your screen (this should "in theory" display the documents colors as if reproduced on that specific printer...) The "dot gain" profiles are often used for newspaper. It compensates for the "closing up" of the printer dots after many runs. I mainly work between Adobe RGB and Working CMYK - US Web Coated.. my2c :) retrocity