Install the latest service release, it improves Python a lot and adds a few new API calls. Then, the additional Python installation could have set some Python related environment variables. Open a DOS-box and enter "set". It will now dump quite a few lines with environment variables. If you see a variable called PYTHONHOME that does not point to Poser/Runtime/Python, you'll have to change it. How to do that depends on your operating system version, see the online help.