The only way I could see NTFS (NT File System) affecting Poser in this way would be if there was some sort of permission-related issue or possibly a bad sector or other hard drive flaw. FAT32 (File Allocation Table 32) does not have the permission overhead and would allow any user to use any file on the FAT32 partition. Both NTFS and FAT32 are methods of making the hard drive surface readable to the Operating System and software.