Yes it'll run from wherever you install it. Mine runs on my D: drive. (My install folder is already bigger than my entire C: partition.) As far as I'm aware it still uses the default swapfile on C: though. Unless one of the gurus knows different. :o).

Expert in computer code including, but not limited to, BTW; IIRC; IMHO; LMAO; BRB; OIC; ROFL; TTYL. Black belt in Google-fu.