My PenPertner (now on the scrap heap infavor of a graphire) did that a long time ago. It seemed like a ctach 22 It wouldn't load the driver without detecting the pen and it couldn't detect the pen because the driver didn't load. I found the main exe that rand the pen (Seems like it was tablet.exe) ran that. The pen snapped to life. Then while the pen was working I reinstalled the driver and it successfully detected the pen and cam back to life. Wacom said it was some weird com port problem. P.S. My graphire has never done any thing but work perfectly.