A lot depends on how large your texture folder is, and what shape it's in - I fixed a Poser Lockup problem once when I noticed my textures folder was taking up 700+Gigs on a 60Gig drive - ran disk utilities to repair the corrupted folder entries, then defragged, and the problem went away. Disk Diags & Defrags seem always to be a good idea when looking into a poser problem.