Nevada, I use Photoshop and Poser simultaneously and have had no problems with either of them. As was mentioned already, it only requires you have a processor big enough to run them, since both are rather large programs. Poser especially can grow to be a monsterous program once you start adding props, characters, textures, and etc. I think its just a matter of preference as to whether you like PSP or Photoshop, and Poser or Bryce. Many artists here use a variety of combinations of the above. Best of Luck, CM