Here's some things I came across so far that may be of interest :

First a good quirk: I upped my athlon64x2 from 2.0GHz to 2.2GHz and changed my RAM timing from 5-5-5-15 to 4-4-4-12, and somehow my rendering speed increased by almost 30%.  I redid the test many times to be sure.  Strange but good.

Second quirk: If you ever try to save a corrupt object to a presets folder it can wipe out that entire preset folder, and you won't know it until it happens.  Lucky I had a backup of that objects folder.

Third quirk:  When manipulating a complex grouped model, suddenly one of the subgroups can shift position unexpectedly and for no apperent reason.  Lucky I had a backup of my model.

Fourth quirk:  Some scenes would continually crash in a terrible way right in the middle of manipulation. When I changed the names of imported objects to simpler names, the crashes went away.  It appears that long, complex object names caused the crashes, but I'm still not 100% sure.

The bottom line... Bryce away but be careful!

"An Example is worth Ten Thousand Words"