I have carefully creased the smile lines on a facial morph target by putting loops near each other.  Later when sculpting (smoothing) the cheeks, I find the creases smoothed out. I have tried several times to avoid touching the creases but always have to go back and redo the creases.

My question is: is there some way in Blender 2.45 to lock the vertices you are happy with, from being affected by latter tweaking. The closest thing I have come up with is hiding vertices in Edit mode and using proportional editing. Unfortunately, this is difficult once you make the surrounding area invisible.

Attached Link: Nicholasbishop

dono if its possible, did you try puting them in a diffrent vertex group If that doesnt work try contacting the developper Nicholasbishop of the sculpting part and sugest such a feature , I think it would be realy usefull.

for some free stuff i made
and for almost daily fotos

This isn't really a solution, but I suggest that, in the future, do the sculpting first and then the creases.

It is better to do one thing well, than to do many things and excel at nothing.

Thanks for your replies. 

Since I am doing a Poser morph, you can't break up the vertices.  Otherwise I would have used Blender's crease marker/modifier.  I'll try and get a hold of Nicholasbishop and suggest the feature.