A 13 minute test render using an exr file for the environment map, the dome and scene settings, and an overhead umbrella lamp for Poser Reality with the Iray emitter shader.

The shirt is from Cyberpunk for M4 and the hair is Punk for Genesis.  I didn't change the shirt settings other than to use the Iray base to set the displacement to 2.  I set the hair's smoother up a few notches and added extra spec settings.

The Iray base for the skin, and some serious tweaks in the bump, displacement, etc.  The eye surface is the thin glass from Iray, tears are thin water and the cornea is thin glass with 1.45 refraction.

Not bad, considering my Studio renders end up cooking for hours with the settings I tend to use.  I'm going to let this cook overnight (I need sleep) to see how well it will get the bits of artifacts out in this.