After a series of disasters struck earth including nuclear war, a plaque that killed off most of the male population and altered the birthrate so that women now outnumber men 6 to 1, and alien invasions the survivors were beginning to reestablish the domination of human on earth. This time women were in charge and men were kept in the home, subservient to women. Orders of nuns sprang up, like the order of knights from the middle age. They traveled the world on the motorcycles confronting and destroying all that was evil. Mary Mayhem was a novice in the order of Madonna. This is her first solo mission. She stops to investigate a building on the outskirts of the bombed out city of New Orleans.