I've rendered out the following animation
http://www.youtube.com/watch?v=y3YX5NHeN2k

I know YouTube is terrible quality, but if you can tell there's a keyframe where the orientation changes so that the large Mosque is in sight.  When I render this out at Broadcast quality, there seems to be a little chunk/jolt of the camera.  I have a keyframe at around 3 seconds which is the reason for this jolt.  I've tried changing the function on the keyframes to Ease-in-ease-out, but it still gives me a little jerk.  I have the animation set to Smooth in the Animation Toolbox.  I've also tried Basic, but I still can't get rid of this! 

Help?  Is this a problem with Vue camera movement?  Or am I missing something else that could help smooth out this rotation?

I've just never used the animation part of Vue - animations can be cool, definitely, but just working with only one computer, the calculation of good looking anims is too time consuming for me ...

Anyway - looking at your animation, the rough part seems to be concentrated to that part in the anim, where the camera view is pointing totally at a lot of details covering the whole frame size and that in close distance.

Once the view moves into the sky area, and the objects are getting further away, meaning the details per pixel are far less to be calculated and the animations gets smoother.

Maybe you have to double or triple the frames to be calculated during this first period of camera movement and later you have to rework the movie in a good video processing program and recalculate the speed there - this way there would be enough frames for the processing program to drop every few frames and get to the right speed for that beginning part of the anim.

I know, this would be just a work-around, but i'm not even a beginner in Vue animation ... sorry.

YouTube's jitteriness (at least on my connection) is making it hard for me to see the exact jump you're talking about, but my first question would be whether you've assigned the "helicopter" motion type to your camera. I've experienced bumps like the one you describe when I've used that setting. I haven't figured out how to fix it, but as a first step toward solving your problem, try switching the motion type to something else.