I recently upgraded to Poser 13 from Poser 11 and experienced many of the same issues I did with the User Interface when I first installed Poser 11.  Namely, the menu items are too tiny to read.  Adjusting the scaling in the user interface, kinda works, but it still leaves many of the menu items too small for my old eyes.

The "fix" I found for Poser 11 on my Windows 11 machine (which may help new users with Poser 13) requires opening the Properties window for Poser 13, then click on the Compatibility tab. The click the option for changing the high DPI settings, then overriding DPI options to allow the System (Enhanced) to set the DPI. Apparently, with higher resolution displays, scaling the program is hard (I don't understand much of the gobbly-gook descriptions of this on the Internet), but this worked for me. It also fixed the problem of teeny-tiny menus and I could change the user interface scaling back to 1 (the default) rather than 2.50 to read the menu items.

These are the Wundows 11 menus you need to find ...

Also works in recent versions of Windows 10. A lot nicer that they added that setting than the old fix that required manifests.